Strand Life Sciences, formerly Strand Genomics, is a Bengaluru, India-based in silico technology company. Strand focuses in data mining, predictive modeling, computational chemistry, software engineering, bioinformatics, and research biology to develop software and services for life sciences research. Strand also offers custom solutions based on its intellectual property. In August 2007, Strand and Agilent Technologies, Inc. entered an agreement in which Strand develops and supports Agilent's GeneSpring software which Agilent obtained through Silicon Genetics acquisition in August 2004. In October 2010, Strand and Agilent renewed the agreement for Strand to expand the scope of Agilent's GeneSpring across multiple life sciences disciplines.
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History
Strand Life Sciences was founded in October 2000 by Professors Vijay Chandru, Ramesh Hariharan, Swami Manohar, and V. Vinay. It was registered as Strand Genomics, but was later renamed to Strand Life Sciences as it dealt with various other aspects of life sciences. In August 2007, Strand and Agilent Technologies, Inc. entered an agreement in which Strand develops and supports Agilent's GeneSpring software which Agilent obtained through Silicon Genetics acquisition in August 2004. In October 2010, Strand and Agilent renewed the agreement for Strand to expand the scope of Agilent's GeneSpring across multiple life sciences disciplines.
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Software
Strand NGS (formerly Avadis NGS)
Strand NGS is a software platform for next-generation sequencing data analysis. It can import raw read sequences from sequencing platforms like Illumina, Ion Torrent, PacBio, ABI, and 454 Life Sciences and supports fragment, single-end, paired-end, mate-paired, directional single/ paired end library types. Raw reads in formats FASTA, FASTQ, SAM, BAM, Unaligned BAM, BED, Counts data, VCF, VAL, or Eland formats can be imported into the tool. In addition, perform split read alignment for detecting long InDels and translocations.
Strand NGS also allows users to perform quality control on the imported data and filter reads before the main analysis is performed. Version 2.6 of the tool supports six experiment types: ChIP-Seq, RNA-Seq, small RNA, Methyl-Seq, MeDIP-Seq and DNA-Seq. Gene, transcript, SNP, homology, gene ontology (GO), and other annotations needed for analysis can be downloaded directly from within Strand NGS website.
Visualization tools, namely Genome Browser, Gene View, and Variant Support View, are a key aspect of the software. Other visualizations available with tool are scatter plot, MvA plot, profile plot, histogram, heat map, box and whisker plot, and Venn diagram. Aided with visualizations, users a pictorial feel for statistical trends in the data.
Strand NGS also provides access to organism-specific interaction databases containing relations between proteins, small molecules, enzymes, complexes, biological processes, molecular functions, and gene families. The two million interactions present in these databases can also be augmented by importing pathways in GPML format (WikiPathways), XML format (BioCyc), BioPAX format from Reactome, Cancer Cell Map, etc. Gene lists generated by analysis steps can be used as the starting point for many pathway analysis operations.
GeneSpring
GeneSpring GX (version 9.0.0 onwards), GeneSpring Workgroup (version 7.0.0 onwards), and Mass Profiler Pro are developed by Strand's R&D division in Bangalore.
Avadis
Avadis is a comprehensive data mining and visualization platform. It combines the power of scalable algorithms and dynamic interactive visualization. The platform was customized for various scientific domains like gene expression, next-generation sequencing, pre-clinical research, chemistry and healthcare.
Sarchitect
Sarchitect is a platform for modeling and predicting drug-relevant properties of molecules in silico.
ArrayAssist
ArrayAssist was developed for Stratagene, Inc., based on the Avadis platform. The production was stopped after Stratagene was acquired by Agilent Technologies, Inc. in 2007.
Accolades
- Strand is a Red Herring "Asia 100 Private Company" for the years 2005 and 2010.
- Deloitte Fast 50 India and Fast 500 Asia in 2009 and 2010.
- Strand Life Sciences named as "NASSCOM IT Innovator 2006" by NASSCOM. It is one amongst seven Indian companies to be recognized by NASSCOM as IT Innovators in 2007.
- Strand Life Sciences named as "Technology Pioneer 2007" by the World Economic Forum.
- Strand has received the Frost & Sullivan "Excellence in Technology Award 2005" for its technology platform Avadis.
- 2003 Strand was nominated as a technology pioneer by the World Economic Forum for the year 2002.
- Genome Technology Magazine nominated Strand as the top five most important companies in the category "Company of the Year 2002".
Source of the article : Wikipedia
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